Disruptive Natural selection

Disruptive selection favors the survival of individuals at both extremes of a range, rather than the  intermediate.

Increase variance in the population because select those phenotype which are away from mean.

It maintain balance polymorphism and maximum selection coefficient value.

TLS Online TPP Program

#Id: 8372

#Section 3: Genetics, Cellular and Molecular Biology

Thick-filament regulation

Myosin-dependent mechanism regulate contraction in smooth muscle and non-muscle cells.

TLS Online TPP Program

#Id: 9213

#Section 3: Genetics, Cellular and Molecular Biology

Probability of being heterozygote in given population

H = 1 - 1/2N

TLS Online TPP Program

#Id: 10330

#Section 2: General Biology

The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex. 

TLS Online TPP Program

#Id: 8623

#Section 3: Genetics, Cellular and Molecular Biology

SCF and APC/C are multisubunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin-protein ligases.

TLS Online TPP Program

#Id: 8176

#Section 3: Genetics, Cellular and Molecular Biology

SNARE complex is disassembled by ATP-dependent reaction mediated by cytosolic proteins, NSF & α-SNAP