Loss of their original diversity per generation

=1/2n

Gain of their original diversity per generation

=1/2n 

Gain or Loss of their original diversity per generation

=1/4n

TLS Online TPP Program

#Id: 8598

#Section 3: Genetics, Cellular and Molecular Biology

Labile factors called cyclins drive the progression of cells through different stages of the cell cycle by binding to CDKs.

TLS Online TPP Program

#Id: 8599

#Section 3: Genetics, Cellular and Molecular Biology

Cells commit to a new cell division at a specific point in G1 known as START or the restriction point.

TLS Online TPP Program

#Id: 8600

#Section 3: Genetics, Cellular and Molecular Biology

R-factor 

In mammalian cells - cyclin D 

In yeast - Cln3

TLS Online TPP Program

#Id: 8601

#Section 3: Genetics, Cellular and Molecular Biology

TLS Online TPP Program

#Id: 8602

#Section 3: Genetics, Cellular and Molecular Biology

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8603

#Section 3: Genetics, Cellular and Molecular Biology

G1 Cyclin–CDKs

In human - cyclin D-CDK 4 

cyclin D-CDK 6

In budding yeast - CIn 3-Cdc 28