Penicillin is produced by P. chrysogenum in a fed-batch culture with the intermittent addition of glucose solution to the culture medium. The initial culture volume at quasi-steady state is V0 = 500 l, and glucose-containing nutrient solution is added with a flow rate of F = 50 l/h. Glucose concentration in the feed solution and initial cell concentration are S0 = 300 g/l and X0 = 20 g/l, respectively. The kinetic and yield coefficients of the organism are mm = 0.2 h-1 , KS = 0.5 g/l, and YX/S = 0.3 g dw/g glucose. If qP = 0.05 g product/g cells h and P₀ = 0.1 g/l, determine the product concentration in the vessel at t = 10 h

TLS Online TPP Program

#Question id: 2968

#Section 3: Genetics, Cellular and Molecular Biology

What is the name of the microtubule-organizing center found in animal cells as an identifiable structure present during all phases of the cell cycle?

TLS Online TPP Program

#Question id: 2976

#Section 3: Genetics, Cellular and Molecular Biology

Match the following Regulators with its functions.

Column I	Column II
A.  Wee1 kinase	i. Degradation of phosphorylated Sic1 or p27KIP1
B. Cdc25A phosphatase	ii. Induces degradation of B-type cyclins
C. APC/CCdc20	iii. Activates vertebrate S phase CDKs
D. SCF	iv. Inhibits CDKs

Which of the following is correct?

TLS Online TPP Program

#Question id: 2987

#Section 3: Genetics, Cellular and Molecular Biology

Following statements are regarding the goals of gap phases.

(i) to prepare for the next phase of the cell cycle.

(ii) to check that the previous phase of the cell cycle has been completed appropriately.

(iii) to inhibits CDKs activity.

(iv) to enhance servillance mechanisms.

Which of the following is correct?

TLS Online TPP Program

#Question id: 2994

#Section 3: Genetics, Cellular and Molecular Biology

If a cell has completed meiosis I and the first cytokinesis, and is just beginning meiosis II, which of the following is an appropriate description of its genetic contents?

TLS Online TPP Program

#Question id: 2995

#Section 2: General Biology

 Which of the following incorrect pair?

TLS Online TPP Program

#Question id: 2996

#Section 2: General Biology

Cell death approximately equal to cell division is found in