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TLS Online TPP Program

#Question id: 2105

An investigator wants to use FRAP to quantify the lateral movement of a specific plasma membrane protein, but to do so this investigator must first:

#Section 2: General Biology

  1. focus a laser on one region of the cell surface.

  2. measures the intensity of the fluorescence of the cell surface.

  3. label the cell with a fluorescent reagent that binds specifically to the cell surface.

  4. add detergents to make the cell surface more fluid.

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TLS Online TPP Program

#Question id: 3806

#Section 3: Genetics, Cellular and Molecular Biology

How are damaged nucleotides recognized by DNA repair enzymes?
TLS Online TPP Program

#Question id: 3808

#Section 3: Genetics, Cellular and Molecular Biology

Fibroblast cells from several different xeroderma pigmentosa patients were cultured, then fused in intergenic complementation studies. Which cell fusions would not result in a hybrid capable of repairing damaged DNA?
TLS Online TPP Program

#Question id: 3809

#Section 3: Genetics, Cellular and Molecular Biology

MMR is a highly conserved biological pathway. Several human MMR proteins have been identified based on their homology to E. coli MMR proteins. Match the following

Human

Function

1. MSH2-MSH6

A. DNA mismatch/damage recognition

2. MLH-PMS

B. Molecular matchmaker

3. MutH

C. Strand discrimination

D. Absent in Human


TLS Online TPP Program

#Question id: 3811

#Section 3: Genetics, Cellular and Molecular Biology

The mechanism of DNA replication is studied in an E. coli replication fork. Which is a characteristic of this replication fork?
TLS Online TPP Program

#Question id: 3848

#Section 3: Genetics, Cellular and Molecular Biology

are small molecules that function as adapters between amino acids and codons.
TLS Online TPP Program

#Question id: 3849

#Section 3: Genetics, Cellular and Molecular Biology

Which of the following is short 20 to 22-nucleotide single-stranded RNAs that block the expression of complementary or partially complementary mRNAs.