TLS Online TPP Program

#Question id: 2003


The number of MHC protein combinations possible in a given population is enormous. However, an individual in that population has only a couple of MHC possibilities. Why?

#Section 2: General Biology
  1. The MHC proteins are made from several different gene regions that are capable of rearranging in a number of ways.

  2. MHC proteins from one individual can only be of class I or class II.

  3. Each of the MHC genes has a large number of alleles, but each individual only inherits 2 for each gene.

  4. Once a B cell has matured in the bone marrow, it is limited to two MHC response categories.