TLS Online TPP Program

#Question id: 13106


With the help of DNA fingerprinting which can be used to determine paternity. There are three babies (Baby A, Baby B and Baby C) in a maternity ward, and three sets of confused and worried parents. (Father and Mother #1 are a couple, as are Father and Mother #2, and Father and Mother #3.) 
You do each PCR reaction on chromosome 15 and load each one into a separate well of an agarose gel, and then run the gel.

 
 
Why is it that some people only have one band?

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology
  1. They are homozygotes for the allele that can be cut.
  2. They are homozygotes for the allele that cannot be cut.
  3. They are heterozygotes, and possess one allele that can be cut and one allele that cannot be cut.
  4. The more repeats you have, the longer your DNA fragment.
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TLS Online TPP Program

#Question id: 14134

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

PAM stands for ___

TLS Online TPP Program

#Question id: 14135

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is correct about PAM matrix? 

TLS Online TPP Program

#Question id: 14136

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.

TLS Online TPP Program

#Question id: 14137

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________

TLS Online TPP Program

#Question id: 14138

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.

TLS Online TPP Program

#Question id: 14139

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity?