Following are certain statements regarding furanocoumarins;

 a) furanocoumarins have an attached furan ring

 b) These compounds are toxic until they are activated by sunlight in the ultraviolet A (UV-A) region (320–400 nm)  

 c) Light activated furanocoumarins can insert themselves into the double helix of DNA and bind to the pyrimidine bases, thus blocking transcription and repair and leading eventually to cell death   

 d) Phototoxic furanocoumarins are especially abundant in members of the Umbelliferae family, including celery, parsnip, and parsley.

 Which of the following combination from the above statements is correct?

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#Question id: 14133

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

The study of evolutionary relationships is known as

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#Question id: 14134

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

PAM stands for ___

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#Question id: 14135

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is correct about PAM matrix? 

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#Question id: 14136

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about global alignment? 

(A) Global alignment is based on the Needleman–Wunsch algorithm.

(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.

(C) It is only suitable for aligning two closely related sequences that are of the same length.

(D) GAP is a web-based pairwise global alignment program.

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#Question id: 14137

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Consider the following alignment of two DNA sequences:

                            AGTAAC

                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________

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#Question id: 14138

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 

Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.