The series 

TLS Online TPP Program

#Question id: 15112

#Section 1: Engineering Mathematics

TLS Online TPP Program

#Question id: 14249

#Section 5: Bioprocess Engineering and Process Biotechnology

Aspartase enzyme is used industrially for manufacture of aspartic acid, a component of low-calorie sweetener. Fumaric acid and ammonia are converted to aspartic acid according to the equation:

 

                                        

Under investigation is a process using aspartase in intact Bacillus cadaveris cells. In the substrate range of interest, the conversion can be described using Michaelis-Menten kinetics with K m 4.0 gl^-1. The substrate solution contains 15% (w/v) ammonium fumarate; enzyme is added in the form of lyophilised cells and the reaction stopped when 85% of the substrate is converted. At 32⁰C vmax for the enzyme is 5.9 g l^-1h^-1 and its half-life is 10.5 d. At 37⁰C Vmax increases to 8.5 g l^{- 1} h^{- I} but the half-life is reduced to 2.3 d. The average downtime between batch reactions is 28 h. calculate the reactor volume required to produce 5000 tonnes of aspartic acid per year

TLS Online TPP Program

#Question id: 2083

#Section 2: General Biology

Sphingolipids are considered amphipathic glycolipids if:

TLS Online TPP Program

#Question id: 1845

#Section 2: General Biology

BCG is used to protect against:

TLS Online TPP Program

#Question id: 1170

#Section 3: Genetics, Cellular and Molecular Biology

A gain-of-function mutation in which of the following would promote malignancy in cells whose proliferation is inhibited by TGFβ?