TLS Online TPP Program

#Question id: 4703


Within a few weeks of treatment with the drug 3TC, a patientʹs HIV population consists entirely of 3TC-resistant viruses. How can this result best be explained?

#Section 2: Evolution
  1. HIV can change its surface proteins and resist vaccines.

  2. The patient must have become reinfected with 3TC-resistant viruses.

  3. HIV began making drug-resistant versions of reverse transcriptase in response to the drug.

  4. A few drug-resistant viruses were present at the start of treatment, and natural selection increased their frequency.