The freed C-terminal is not involved in signaling and is often degraded, whereas the N-terminal becomes the active Hedgehog protein intended for secretion

TLS Online TPP Program

#Id: 7039

#XL - T Zoology

Gradualism is Darwin’s proposition that the differences between even radically different organisms have evolved by small steps through intermediate forms, not by leaps

TLS Online TPP Program

#Id: 7033

#XL - T Zoology

TLS Online TPP Program

#Id: 9466

#XL - T Zoology

Binding resembles the insertion of a two-pronged “plug” the phosphotyrosine and isoleucine side chains

of the peptide into a two-pronged “socket” in the SH2 domain.

TLS Online TPP Program

#Id: 5376

#XL - T Zoology

Some animals can become trap-happy, particularly if the traps are baited with food. This would result in an underestimate of the population size.

TLS Online TPP Program

#Id: 363

#XL - R Botany

When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.