In resting cells,

NF-κB binds directly to an inhibitor called I-κBα

TLS Online TPP Program

#Id: 1352

#XL - T Zoology

GRB2 SH3 domains bind to proline-rich sequences in Sos

  

TLS Online TPP Program

#Id: 1353

#XL - T Zoology

GRB2 SH2 domain binds to a specific phosphotyrosine residue in the cytosolic domain of an activated RTK.

 

TLS Online TPP Program

#Id: 1354

#XL - T Zoology

The SH2 domain binds strongly to any peptide containing a critical four-residue core sequence:  phosphotyrosine–glutamic acid–glutamic acid–isoleucine

TLS Online TPP Program

#Id: 1355

#XL - T Zoology

MEK, a dual-specificity protein kinase

TLS Online TPP Program

#Id: 9032

#XL - T Zoology

TLS Online TPP Program

#Id: 9033

#XL - T Zoology