After dimerization MyD88 proteins bind to the IL-1R through the TIRs, and facilitates the binding of many copies of the kinases IRAK4 and IRAK1 or IRAK2

TLS Online TPP Program

#Id: 10106

#XL - T Zoology

Focal adhesions 

Adhesion type- Cell-matrix

Adhesion receptors- Integrins

Cytoskeletal attachment- Actin filaments

TLS Online TPP Program

#Id: 10107

#XL - T Zoology

Focal adhesion

Function- Shape, signaling, force transmission, cell movement

TLS Online TPP Program

#Id: 10108

#XL - T Zoology

Tight junctions seal off body cavities and restrict diffusion of membrane components

TLS Online TPP Program

#Id: 10109

#XL - T Zoology

Tight junctions prevent the diffusion of: 

Macromolecules

Small water-soluble molecules

Ions

Membrane proteins 

Glycolipids

TLS Online TPP Program

#Id: 10110

#XL - T Zoology

Ca2+-dependent cadherin- mediated adhesion also plays an important role in tight-junction formation, stability, and function

TLS Online TPP Program

#Id: 10111

#XL - T Zoology

Gap junctions permit the passage of molecules as large as 1.2 nm in diameter (molecules smaller than 1200 Da).