Monoclonal Antibodies Against Immune Checkpoint Molecules to Treat Cancers

TLS Online TPP Program

#Id: 9504

#XL - R Botany

Xanthomonas, produces TAL (transcription activator‐like) effectors contribute to disease formation or trigger defense by binding host DNA and activating effector‐specific host genes.

TLS Online TPP Program

#Id: 9505

#XL - R Botany

PthXo1, a TAL effector of the rice pathogen Xanthomonas oryzae, activates expression of the rice gene Os8N3, allowing Xanthomonas to colonize rice plants.

TLS Online TPP Program

#Id: 9506

#XL - R Botany

P. syringae pv. Syringae (Pss) secrete syringolin A (SylA), a peptide derivative synthesized by a mixed nonribosomal peptide synthetase/polyketide synthetase encoded by a gene cluster. 

TLS Online TPP Program

#Id: 9507

#XL - R Botany

The effector SylA is secreted by the bacteria into the host plant cells. Once inside the cells, SylA irreversibly inhibits the proteasome

TLS Online TPP Program

#Id: 9508

#XL - R Botany

Fusicoccum amygdali produces the toxin fusicoccin, which targets the plasma membrane H+‐ATPase in many plant species

TLS Online TPP Program

#Id: 9509

#XL - R Botany

Sclerotinia sclerotiorum is a necrotrophic fungus that infects over 400 plant species. It secretes the phytotoxin oxalic acid to assist the early phases of the infection