T-independent response

Type 1 T-independent (TI-1) antigens bind to B cells through both Ig and innate immune receptors. LPS from Gram negative organisms binds to B cells via both mIg and TLR, resulting in signaling from both receptors. 

TLS Online TPP Program

#Id: 8949

#XL - T Zoology

TLS Online TPP Program

#Id: 1313

#XL - T Zoology

Two large classes of GTPase switch proteins-

Heterotrimeric G proteins

Monomeric G proteins

TLS Online TPP Program

#Id: 1314

#XL - T Zoology

GTP-binding switch proteins contains two domain-

Switch I- Thr-35

Switch II- Gly-60 

TLS Online TPP Program

#Id: 1315

#XL - T Zoology

GTPase superfamily of proteins- eIF2, EF1α, EF2, Ran, Sar, Rab, Rho, Rac, Cdc42

TLS Online TPP Program

#Id: 1316

#XL - T Zoology

G protein coupled receptor contains seven membrane-spanning α helices & heterotrimeric G protein.

TLS Online TPP Program

#Id: 1317

#XL - T Zoology

Muscarinic acetylcholine receptor is coupled to a Gαi protein.