Reproduction

sexual reproduction-  by fusion of two gametes

Isogamous (Spirogyra), Anisogamous (Chlamydomonas) or Oogamous (Volvox).

TLS Online TPP Program

#Id: 8226

#XL - Q Biochemistry

I-cell disease

• almost all of the hydrolytic enzymes are missing from the lysosomes of many cell types.

• mis-sorting has been traced to a defective or missing GlcNAc phosphotransferase.

TLS Online TPP Program

#Id: 8225

#XL - Q Biochemistry

Hurler’s disease- mutation in a structural gene that codes for an individual lysosomal hydrolase.

TLS Online TPP Program

#Id: 8224

#XL - Q Biochemistry

Lysosomal storage diseases:

• Hurler’s disease

• Inclusion-cell disease

TLS Online TPP Program

#Id: 8223

#XL - Q Biochemistry

Retromer

a coat protein complex specialized for endosome-to-TGN transport, recycle the M6P receptor to the TGN

TLS Online TPP Program

#Id: 8221

#XL - Q Biochemistry

The M6P receptor protein binds to M6P at pH 6.5–6.7 in the TGN lumen and releases it at pH 6, in the lumen of endosomes.

TLS Online TPP Program

#Id: 8219

#XL - Q Biochemistry

M6P residues are generated in the cis-Golgi by two Golgi-resident enzymes. 

1. N-acetylglucosamine (GlcNAc) phosphotransferase
2. Phosphodiesterase