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III. Vascular plants (pteridophyta)

EVOLUTION OF ROOTS

Instead of the rhizoids seen in bryophytes, roots evolved in the sporophytes of almost all vascular plants

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The adhesiveness of cadherins depends on the presence of extracellular Ca2+

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Two type of Cadherins:
1. Classical cadherin proteins
2. Nonclassical cadherin proteins

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Extracellular region of a classical cadherin contains five copies of the cadherin domain separated by flexible hinge regions

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Ca2+ ions bind to sites near each hinge and prevent it
from flexing, so that the whole string of cadherin domains behaves as a rigid and slightly curved rod to generate cell–cell adhesion

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Each classical cadherin molecule contains: 
A single TM domain
A short C-terminal cytosolic domain
Five extracellular “cadherin” domains (EC1–EC5)

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Three classes of classical cadherins: 
E-cadherin -present on epithelial cells
N-cadherin - present on nerve, muscle and lens cells
P-cadherin - present on cells in the placenta & epidermis

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