Root apical meristem

Growth  occurs  just  behind  the  tip  in  three  overlapping  zones  of  cells at  successive  stages of  primary  growth.  These  are  the  zones  of  cell  division,  elongation, and differentiation

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If Amphitelic attachment occur  Microtubules pull kinetochores; cohesins resist this pulling force. The resulting tension leads to the outer kinetochore component Ndc80 being pulled away from the protein kinase Aurora B

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The Aurora protein kinase family members Aurora A and Aurora B and their associated regulatory factors sense kinetochores that are not under tension and sever these microtubule attachments

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Labile factors called cyclins drive the progression of cells through different stages of the cell cycle by binding to CDKs.

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Cells commit to a new cell division at a specific point in G1 known as START or the restriction point.

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R-factor 

In mammalian cells - cyclin D 

In yeast - Cln3

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