When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.

TLS Online TPP Program

#Id: 9332

#XL - T Zoology

In bright light, little transducin is found in the outer segment, and abundant arrestin is found there; in this condition,vision is relatively insensitive to small changes in light.

TLS Online TPP Program

#Id: 9333

#XL - T Zoology

An evolutionarily conserved family of receptor serine kinases - TGF-β receptor family

TLS Online TPP Program

#Id: 9334

#XL - T Zoology

An evolutionarily conserved family of signaling molecules, TGF-β superfamily includes: 

TGF-β family, Nodal and activin families, BMPs, Vg1 family, GDNF, AMH

TLS Online TPP Program

#Id: 9335

#XL - T Zoology

Drosophila homolog of TGF-β = Dpp

TLS Online TPP Program

#Id: 9336

#XL - T Zoology

Kinase domains in TGF-β receptors phosphorylate and trigger the activation of a conserved class of transcription factors - Smads

TLS Online TPP Program

#Id: 9337

#XL - T Zoology

Principal function of all 3 human TGF-β isoforms, TGF-β1, 2, and 3:

Prevent cell proliferation by inducing the synthesis of p15 INK4B