When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.

TLS Online TPP Program

#Id: 10072

#XL - T Zoology

Epithelial-to-mesenchymal transition is associated with a reduction in the expression of E-cadherin.

TLS Online TPP Program

#Id: 10073

#XL - T Zoology

Snail suppresses the expression of E-cadherin is associated with the EMT

TLS Online TPP Program

#Id: 10074

#XL - T Zoology

A cadherin-family member CDHR3, highly expressed in epithelial cells in the human airway, as a receptor for RV-C (virulent class C rhinoviruses).

TLS Online TPP Program

#Id: 10075

#XL - T Zoology

In cultured cells, C → Y mutation in the EC5 domain of CDHR3 increases the cell-surface expression of CDHR3 and the binding and replication of RV-C.

TLS Online TPP Program

#Id: 10076

#XL - T Zoology

Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. 

TLS Online TPP Program

#Id: 10077

#XL - T Zoology

An integrin molecule is composed of two noncovalently associated transmembrane glycoprotein subunits called α and β.