When the fitness interests of two individuals are different, they are in conflict.

The evolution of cooperation and conflict depends on when these kinds of behaviors are favored by natural selection.

TLS Online TPP Program

#Id: 7932

#XL - Q Biochemistry

Signal sequence

ER targeting sequence, located at the N-terminus of the protein

TLS Online TPP Program

#Id: 7931

#XL - Q Biochemistry

Microsomes

when cells are homogenized, the rough ER breaks up into small closed vesicles with ribosomes on the outside

TLS Online TPP Program

#Id: 7930

#XL - Q Biochemistry

Secretory pathway

pathway of protein trafficking that flows through the ER

TLS Online TPP Program

#Id: 7929

#XL - Q Biochemistry

The ER captures selected proteins from the cytosol as they are being synthesized. These are of two types:

Transmembrane proteins

Water-soluble proteins

TLS Online TPP Program

#Id: 7928

#XL - Q Biochemistry

Muscle cells have an abundant, modified smooth ER called the sarcoplasmic reticulum.

The release and reuptake of Ca2+ by the sarcoplasmic reticulum trigger myofibril contraction and relaxation, respectively

TLS Online TPP Program

#Id: 7927

#XL - Q Biochemistry

Function of the ER:

most eukaryotic cells is to sequester Ca2+ from the cytosol (High concentration of Ca2+-binding proteins in the ER facilitates Ca2+ storage)