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Glycoproteins

Proteins with attached carbohydrates

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TLS Online TPP Program

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Innate response elements commonly engaged by encounter with viral PAMPs, such as secretion of type I interferons, inflammasome and NK-cell activation, as well as IL-12 production.

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Mechanisms of humoral and cell-mediated immune responses

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Many Viruses Are Neutralized by Antibodies
Antibodies are particularly effective if they are localized at the site of viral entry into the body.

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Cell-Mediated Immunity against Virus
Both CD8+ TC cells and CD4+ TH1 cells are required components of the cell-mediated antiviral defense.
Activated TH1 cells produce IL-2, IFN-ϒ, and tumor necrosis factor-α.

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IFN-Ï’ acts directly by inducing an antiviral state in nearby cells.

IL-2 acts indirectly by assisting the development of cytotoxic T lymphocyte(CTL) precursors into an effector population.

Both IL-2 and IFN-Ï’ activate NK cells.

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