Nurturing Life Sciences
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Richard hypothesis
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#XL - Q Biochemistry
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Listeria is a food-borne bacterial pathogen has on its surface a protein ActA, which mimics an NPF that efficiently activates the Arp2/3 complex.
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One NPF is called WASp, as it is defective in patients with Wiskott-Aldrich syndrome.
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The major NPF family is characterized by the presence of a region called WCA (WH2, connector, acidic)