RS Configuration 

Atoms of higher atomic number rank above those of lower atomic number (e.g., —OH ranks above —CH3). If the first substituent atoms are identical, the priority is established by the next atom outward from the chiral center (e.g., —CH2OH takes precedence over —CH3).

TLS Online TPP Program

#Id: 9037

#XL - T Zoology

A plot of the amount of ligand bound to the receptor

[RL] versus the amount of free ligand [L] called a

ligand-binding or saturation curve

TLS Online TPP Program

#Id: 9038

#XL - T Zoology

The levels of insulin present in the body and the Kd for binding of insulin to its receptor on liver cells,

1.4 × 10−10 M (0.14 nM). The normal concentration of insulin in the blood is  5 × 10−12 M. 

The fraction of insulin receptors with bound insulin, [RL]/[RT], at equilibrium as 0.0344

TLS Online TPP Program

#Id: 9039

#XL - T Zoology

The tighter the binding of a ligand to its receptor,the lower the concentration of ligand needed to achieve binding to 50 percent of the receptors.

TLS Online TPP Program

#Id: 9040

#XL - T Zoology

GPCR function as GEFs for heterotrimeric G protein.

TLS Online TPP Program

#Id: 9041

#XL - T Zoology

TLS Online TPP Program

#Id: 9042

#XL - T Zoology

Heterotrimeric G proteins directly bind to and are activated by G protein coupled receptors.