formin family members have two adjacent domains:

FH1- rich in proline, landing site for profilin–ATP–G-actin

FH2 - form a dimer and nucleate filament assembly

TLS Online TPP Program

#Id: 8372

#XL - Q Biochemistry

Thick-filament regulation

Myosin-dependent mechanism regulate contraction in smooth muscle and non-muscle cells.

TLS Online TPP Program

#Id: 8371

#XL - Q Biochemistry

In the presence of ATP,  myosin head releases from the actin filament. 

TLS Online TPP Program

#Id: 8370

#XL - Q Biochemistry

In the absence of ATP, the myosin head is firmly attached to the actin filament. 

TLS Online TPP Program

#Id: 8369

#XL - Q Biochemistry

The length of the myosin II neck domain determines the rate of movement.

TLS Online TPP Program

#Id: 8368

#XL - Q Biochemistry

Myosin V

Two heads but does not assemble into filaments

Large and processive

Function- Organelle transport

TLS Online TPP Program

#Id: 8367

#XL - Q Biochemistry

Myosin II

Two heads and assembles into bipolar filaments

Small and non-processive

Function- Contraction