The major NPF family is characterized by the presence of a region called WCA (WH2, connector, acidic)

TLS Online TPP Program

#Id: 9071

#XL - T Zoology

Feedback mechanisms suppress signaling by the PKA pathway:

1. Intrinsic GTPase activity of Gαs

2. PDE acts to hydrolyze cAMP to 5′-AMP

3. By BARK

TLS Online TPP Program

#Id: 8608

#XL - R Botany

There are three D cyclins in mammals:

cyclins D1, D2, and D3

TLS Online TPP Program

#Id: 1350

#XL - T Zoology

KSR (Kinase suppressor of Ras) is a pseudogene homolog of RAF Involve in the activation of RAF

TLS Online TPP Program

#Id: 9271

#XL - R Botany

TLS Online TPP Program

#Id: 9651

#XL - T Zoology

Phosphorylation by MEK at Y-185 and T-183 in activation loop of MAP kinase leads to a marked conformational change & promotes MAP kinase activation and dimerization.