PKA always phosphorylates a serine or threonine residue that is located within the common sequence motif: X-Arg-(Arg/Lys)-X-(Ser/Thr)-Φ

TLS Online TPP Program

#Id: 9640

#XL - T Zoology

The SH3 domains in GRB2 selectively bind to 

proline-rich sequences in Sos

TLS Online TPP Program

#Id: 1348

#XL - T Zoology

RasD or RasONC  Replacement of the normal glycine 12 with any other amino acid (except proline) “locks” Ras in the active GTP-bound state.

TLS Online TPP Program

#Id: 9431

#XL - T Zoology

Bateman put several males and females together in bottles for several days. 

He concluded that the number of offspring sired by a male increased in proportion to the number of females he mated.

In contrast, the number of offspring produced by a female did not increase with the number of males she mated.

TLS Online TPP Program

#Id: 8142

#XL - Q Biochemistry

Retrograde transport

COPI vesicles = cis-Golgi to ER

TLS Online TPP Program

#Id: 10352

#XL - Q Biochemistry

B-cell activation