Nurturing Life Sciences
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#XL - Q Biochemistry
The curvature of the crista junctions is due to a protein complex called MICOS (mitochondrial contact site and cristae organizing system).
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MICOS has an integral membrane protein subunit that homo-oligomerizes and bends the inner membrane to produce high curvature.
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MICOS mediates close juxtaposition of the outer membrane and inner membrane by binding to outer membraneāassociated proteins
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