Within the nucleus, R-Smads are modified by:

Phosphorylation of linker domains

Acetylation of MH1 domains

Dephosphorylation of the C-terminal serines by nuclear

phosphatases

TLS Online TPP Program

#Id: 7853

#XL - T Zoology

Thus, D glucose in aqueous solution exists as an equilibrium mixture of 5 compounds. The pyranose form predominates in solution.

aD glucofuranose (0.5%)

aD-glucopyranose (37%)

aldehydo- -glucose (0.003%)

bD-glucofuranose (0.5%)

bD-glucopyranose (62%)

TLS Online TPP Program

#Id: 9071

#XL - T Zoology

Feedback mechanisms suppress signaling by the PKA pathway:

1. Intrinsic GTPase activity of Gαs

2. PDE acts to hydrolyze cAMP to 5′-AMP

3. By BARK

TLS Online TPP Program

#Id: 9711

#XL - T Zoology

GTP-bound Cdc42, binds to and activates the Ste20 kinase.

TLS Online TPP Program

#Id: 9693

#XL - T Zoology

Active PKB, phosphorylates

and inhibits the GTP→GDP hydrolysis activity of two GAP

proteins - AS160 and RGC

TLS Online TPP Program

#Id: 8848

#XL - R Botany