SOCS-1, binds to the critical phosphotyrosine in the activation loop of an activated JAK2 kinase, inhibiting its catalytic activity

TLS Online TPP Program

#Id: 1328

#XL - T Zoology

β-adrenergic receptors are deactivated by, β-adrenergic receptor kinase (BARK)

TLS Online TPP Program

#Id: 1329

#XL - T Zoology

Phospholipase C is activated by G proteins containing either Gαo or Gαq.

TLS Online TPP Program

#Id: 1330

#XL - T Zoology

Phospholipase C cleaves PI(4,5)P2, generating two second messengers:  IP3 and DAG

TLS Online TPP Program

#Id: 1331

#XL - T Zoology

The principal function of DAG is to activate protein kinase C.

TLS Online TPP Program

#Id: 1332

#XL - T Zoology

Gαq activate α1-Adrenergic receptor

TLS Online TPP Program

#Id: 1333

#XL - T Zoology

Cholera toxin, secreted by Vibrio cholerae Catalyze a covalent modification of the Gαs protein Inhibit GAP activity.