In the most famous example of Lamarck’s theory, giraffes must have stretched their necks to reach foliage above them, and so their necks were lengthened

The longer necks were inherited, and over the course of generations, this process was repeated, and their necks got longer and longer. 

TLS Online TPP Program

#Id: 8337

#XL - Q Biochemistry

Profilin – G-actin nucleotide exchange (ADP to ATP) 

Cofilin – F-actin disassembly

Thymosin B-4 – G-actin monomer sequestering

TLS Online TPP Program

#Id: 8336

#XL - Q Biochemistry

Actin filament treadmilling is accelerated by:

Profilin and Cofilin

TLS Online TPP Program

#Id: 8335

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8334

#XL - Q Biochemistry

Phalloidin 

isolated from Amanita phalloides, binds at the interface between subunits in F-actin, locking adjacent subunits together and preventing depolymerization.

TLS Online TPP Program

#Id: 8333

#XL - Q Biochemistry

Jasplakinolide,

a sponge toxin, enhances nucleation by binding and stabilizing actin dimers and lowering the Cc.

TLS Online TPP Program

#Id: 8332

#XL - Q Biochemistry

Latrunculin, 

a toxin secreted by sponges, binds and sequesters G-actin