Neo-Lamarckism - August Weismann

cut off the tails of mice for many generations and showed that this mutilation had no effect on the tail length of their descendants.

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NO diffuses locally through tissues and activates an

intracellular NO receptor with guanylyl cyclase

activity in nearby smooth muscle cells

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Resulting rise in cGMP activates protein kinase G leading to relaxation of the muscle and vasodilation

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Rod cells sense light with the aid of a light-sensitive GPCR called rhodopsin.

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Rhodopsin has two components: 

Opsin protein, member of the GPCR A family 

11-cis-retinal light-absorbing pigment

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