Neutral theory of molecular evolution

Developed by Motoo Kimura, who argued that most of the evolution of DNA sequences occurs by chance (genetic drift) rather than by natural selection. 

TLS Online TPP Program

#Id: 8900

#XL - R Botany

The Aurora protein kinase family members Aurora A and Aurora B and their associated regulatory factors sense kinetochores that are not under tension and sever these microtubule attachments

TLS Online TPP Program

#Id: 8598

#XL - T Zoology

Labile factors called cyclins drive the progression of cells through different stages of the cell cycle by binding to CDKs.

TLS Online TPP Program

#Id: 8599

#XL - T Zoology

Cells commit to a new cell division at a specific point in G1 known as START or the restriction point.

TLS Online TPP Program

#Id: 8600

#XL - T Zoology

R-factor 

In mammalian cells - cyclin D 

In yeast - Cln3

TLS Online TPP Program

#Id: 8601

#XL - T Zoology

TLS Online TPP Program

#Id: 8602

#XL - T Zoology

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K