Haldane’s rule: Hybrid sterility or hybrid inviability is often limited to the heterogametic sex. 

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A key function of mitotic CDKs, together with other protein kinases and ubiquitin-protein ligases, is to induce the formation of the mitotic spindle, also known as the mitotic apparatus.

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Centrosomes contain γ tubulin, which forms specific ringlike complexes (γ TuRCs) that, have the ability to nucleate microtubules and form a bipolar spindle

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Mitotic spindle attach to chromosomes via specialized protein structures known as kinetochores

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Kinetochores assemble on regions of chromosomal DNA marked by a centromere-specific H3 histone variant called CENP-A.

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Amphitelic attachment, 

sister kinetochores attach to microtubules emanating from opposite spindle poles, they are stably attached

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Merotelic attachment 

A kinetochore can attach to microtubules emanating from both poles at the same time