Molecular Handcuff 

Phosphorylation of Raf is recognize by protein 14-3-3 dimer, which locks the autoinhibitory domain in a position where it blocks and inhibits the kinase active site

TLS Online TPP Program

#Id: 8397

#XL - Q Biochemistry

Z disk 

Thin actin filaments are assembled with their (+) ends embedded in a densely staining structure

TLS Online TPP Program

#Id: 9998

#XL - T Zoology

Wnt/calcium pathway leads to the release of calcium stored within cells, and calcium acts as an important secondary messenger to modulate the function of many downstream targets.

TLS Online TPP Program

#Id: 8602

#XL - T Zoology

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8925

#XL - T Zoology

The protein kinases DNA-PK, ATM, and ATR are activated at sites of damaged DNA

TLS Online TPP Program

#Id: 5382

#XL - T Zoology

Perfect compensation hypothesis