PI-3 kinase adds a phosphate to the 3′ carbon in one of two separate PI substrates, leading to formation of two PI 3-phosphates: PI(3,4)P2 or PI(3,4,5)P3

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Amphitelic attachment, 

sister kinetochores attach to microtubules emanating from opposite spindle poles, they are stably attached

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Merotelic attachment 

A kinetochore can attach to microtubules emanating from both poles at the same time

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Syntelic attachment 

Both kinetochores of a sister chromatid pair can attach to microtubules from the same pole

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Monotelic attachment 

only one kinetochore can attach to microtubules

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Sensing mechanism used by cells to detect incorrect chromosome attachments is based on tension.

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If Amphitelic attachment occur  Microtubules pull kinetochores; cohesins resist this pulling force. The resulting tension leads to the outer kinetochore component Ndc80 being pulled away from the protein kinase Aurora B