Extracellular basic hydroxyproline rich glycoproteins

(HRGPs) via the tyrosine in the repeated motif PPPPY that reacts with H2O2.

TLS Online TPP Program

#Id: 10067

#XL - T Zoology

Ca2+ ions bind to sites near each hinge and prevent it

from flexing, so that the whole string of cadherin domains behaves as a rigid and slightly curved rod to generate cell–cell adhesion

TLS Online TPP Program

#Id: 8167

#XL - Q Biochemistry

Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

TLS Online TPP Program

#Id: 8562

#XL - Q Biochemistry

In neither case does the inhibitor compete with the substrate for the same binding site, so the inhibition cannot be overcome by increasing the substrate concentration.

TLS Online TPP Program

#Id: 9834

#XL - R Botany

Red light-induced Pfr formation initiates the degradation of PIF proteins through phosphorylation, followed by degradation via the proteasome complex

TLS Online TPP Program

#Id: 9044

#XL - T Zoology