When Pr molecules are exposed to red light, most of them absorb it and are converted to Pfr, but some of the Pfr also absorbs the red light and is converted back to Pr because both Pr and Pfr absorb red light. 

TLS Online TPP Program

#Id: 7905

#XL - Q Biochemistry

Mitophagy provides Mitochondrial Quality Control

TLS Online TPP Program

#Id: 7904

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 7903

#XL - Q Biochemistry

Mitochondrial fusion and fission are mediated by a set of GTPase enzymes:

Mitochondrial fusion -MFN1/2 & OPA1

Mitochondrial fission- DRP1

TLS Online TPP Program

#Id: 7902

#XL - Q Biochemistry

Single mutation in the TΨCG loop of the mitochondrial lysine tRNA

“Ragged-red” muscle fibers & uncontrolled jerky movements

TLS Online TPP Program

#Id: 7901

#XL - Q Biochemistry

Deletions in mtDNA cause another set of diseases:

Chronic progressive external ophthalmoplegia

Kearns–Sayre syndrome

TLS Online TPP Program

#Id: 7900

#XL - Q Biochemistry

Leber’s hereditary optic neuropathy

caused by a missense mutation in the mtDNA gene

encoding subunit 4 of the NADH-CoQ reductase