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TLS Online TPP Program

#Id: 9804

PAS-related domain (PRD) repeats mediate phytochrome dimerization. 
The PRD domain targets the Pfr form of phyB to the nucleus, although it lacks a canonical nuclear localization signal (NLS).

#XL - R Botany #Mechanisms of action of Phytochromes #Part B Pointers
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TLS Online TPP Program

#Id: 8153

#XL - Q Biochemistry

A second function of small GTPases in vesicle formation is in the pinching off of a completed vesicle from the parent membrane
TLS Online TPP Program

#Id: 8154

#XL - Q Biochemistry

Sar1 GTPase drives the pinching off of COPII vesicles
ARF GTPase drives the pinching off of COPIvesicles
Dynamin GTPase drives the pinching off of clathrin-coated vesicles
TLS Online TPP Program

#Id: 8156

#XL - Q Biochemistry

Two different kinds of sorting signals:
Membrane cargo proteins carry cytoplasmic sorting signals
Soluble cargo proteins carry luminal sorting signals
TLS Online TPP Program

#Id: 8157

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8158

#XL - Q Biochemistry

Soluble ER-resident proteins contain C-terminal KDEL sorting signal that allows them to be retrieved. 
TLS Online TPP Program

#Id: 8159

#XL - Q Biochemistry

KDEL receptor, located mainly in the cis-Golgi network and in both COPII and COPI vesicles, binds proteins bearing the KDEL sorting signal and returns them to the ER