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Retinoic acid-inducible gene-I-like receptors (RLRs) are soluble PRRs that reside in the cytosol of many cell types.

#XL - T Zoology #Innate Immunity #Part B Pointers
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TLS Online TPP Program

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#XL - T Zoology

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#XL - T Zoology

The extracellular domain of cytokine receptors are constructed of two subdomains, each contains seven conserved β strands folded together

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#XL - Q Biochemistry

β oxidation
In mammalian cells, occurs in mitochondria & peroxisomes.
In yeast and plant cells, occurs in peroxisomes.

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#XL - Q Biochemistry

Two different kinds of sorting signals:
Membrane cargo proteins carry cytoplasmic sorting signals
Soluble cargo proteins carry luminal sorting signals

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#XL - T Zoology

The main physical barriers—the body’s first line of defense—are the epithelial layers of the skin and of the mucosal and glandular tissue surfaces connected to the body’s openings

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