Viral Infections

Virus enters a cell via a cell-surface receptor for which it has affinity and preempts cell biosynthetic machinery to replicate all components of itself, including its genome.

This genome replication step is often error prone, generating numerous mutations.

TLS Online TPP Program

#Id: 7889

#XL - Q Biochemistry

In mitochondria, the metabolism of sugars is complete: allows 15 times more ATP to be made from a sugar than by glycolysis alone.

TLS Online TPP Program

#Id: 7888

#XL - Q Biochemistry

In other cells, mitochondria remain fixed at points of high energy demand.

TLS Online TPP Program

#Id: 7887

#XL - Q Biochemistry

In highly polarized cells, mitochondria can move long distances being propelled along microtubule tracks

TLS Online TPP Program

#Id: 7886

#XL - Q Biochemistry

Mitochondria are associated with the cytoskeleton, which determines their distribution in different cell types.

TLS Online TPP Program

#Id: 7885

#XL - Q Biochemistry

VDAC 

A multifunctional transmembrane channel protein (similar in structure to bacterial porins) allow passing of  ions and most small hydrophilic molecules (up to about 5000 Da).

TLS Online TPP Program

#Id: 7884

#XL - Q Biochemistry

The most abundant protein in the outer mitochondrial membrane is a mitochondrial β-barrel porin called VDAC (voltage-dependent anion channel).