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Original antigenic sin
Tendency to focus an immune attack on those structures that were present during the original.
This means that our immune systems effectively ignore the subtle changes occurring each year in pathogens

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#XL - Q Biochemistry

In animal cells,
Most of the glycosaminoglycans of the extracellular matrix are synthesized in golgi apparatus.

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#XL - Q Biochemistry

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#XL - Q Biochemistry

Three major types of coated vesicles involved in protein trafficking:
1. COPII vesicles
2. COPI vesicles 
3. Clathrin-coated vesicles

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#XL - Q Biochemistry

Anterograde transport
COPII vesicles = ER to Golgi

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Anterograde transport through the golgi occurs by cisternal maturation

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Retrograde transport
COPI vesicles = cis-Golgi to ER

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