Diphtheria

Natural infection with C. diphtheriae occurs only in humans and is spread by respiratory droplets. 

The organism colonizes the nasopharyngeal tract and causes little tissue damage, with only a mild inflammatory reaction. 

TLS Online TPP Program

#Id: 8880

#XL - T Zoology

Active cytoplasmic cyclin B-CDK1 translocates into the nucleus, where it phosphorylates nuclear lamins to cause nuclear envelope breakdown and, together with Plk1 and the Aurora kinases, induces chromosome condensation and formation of the mitotic spindle.

TLS Online TPP Program

#Id: 10387

#XL - Q Biochemistry

Class I presentation requires internal synthesis of virus protein, as shown by the requirement that the target cell be infected by live virus, and by the inhibition of class I presentation observed when protein synthesis was blocked by the inhibitor emetine.

TLS Online TPP Program

#Id: 8172

#XL - Q Biochemistry

Effector proteins of Rab6 is Kinesin

Effector proteins of Rab27 is Type V Myosin

TLS Online TPP Program

#Id: 9982

#XL - T Zoology

Frizzled receptor possesses a unique hydrophobic cleft adapted to interact with lipidated Wnts, a binding conformation mimicked in Notum’s structure as well.

TLS Online TPP Program

#Id: 10668

#XL - R Botany

Intercalary meristem

They occur in grasses and regenerate parts removed by the grazing herbivores