Diphtheria

Natural infection with C. diphtheriae occurs only in humans and is spread by respiratory droplets. 

The organism colonizes the nasopharyngeal tract and causes little tissue damage, with only a mild inflammatory reaction. 

TLS Online TPP Program

#Id: 8143

#XL - Q Biochemistry

Vesicle Type- COPII

Transport - ER to cis-Golgi 

Coat Proteins - Sec23/Sec24 and Sec13/Sec31, Sec16

Associated GTPase- Sar1

TLS Online TPP Program

#Id: 8142

#XL - Q Biochemistry

Retrograde transport

COPI vesicles = cis-Golgi to ER

TLS Online TPP Program

#Id: 8141

#XL - Q Biochemistry

Anterograde transport through the golgi occurs by cisternal maturation

TLS Online TPP Program

#Id: 8140

#XL - Q Biochemistry

Anterograde transport

COPII vesicles = ER to Golgi

TLS Online TPP Program

#Id: 8139

#XL - Q Biochemistry

Three major types of coated vesicles involved in protein trafficking:

1. COPII vesicles

2. COPI vesicles 

3. Clathrin-coated vesicles

TLS Online TPP Program

#Id: 8138

#XL - Q Biochemistry