Frizzled receptor possesses a unique hydrophobic cleft adapted to interact with lipidated Wnts, a binding conformation mimicked in Notum’s structure as well.

TLS Online TPP Program

#Id: 8623

#XL - R Botany

SCF and APC/C are multisubunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin-protein ligases.

TLS Online TPP Program

#Id: 8915

#XL - T Zoology

Mitotic exit network plays an important role in shutting off mitotic cyclins by controlling the activation of the Cdc14 phosphatase through a GTPase pathway.

TLS Online TPP Program

#Id: 8396

#XL - Q Biochemistry

Each sarcomere contains two major types of filaments: 

Thick filaments (myosin II)

Thin filaments (actin and associated proteins)

TLS Online TPP Program

#Id: 8117

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8540

#XL - Q Biochemistry

Dynein-related transport requires dynactin, that links dynein to its cargo