TLS Online TPP Program

#Question id: 2114


A research team is working on the design of a new drug for the treatment of lung cancer. To be most effective, this drug must specifically enter the cytoplasm of lung cells while not entering the cells of other tissues. Which of the following characteristics would likely enhance the specificity of this drug?

#XL - S Microbiology
  1. the relative hydrophobicity of the drug molecule

  2. phospholipid composition of lung cell plasma membranes

  3. specificity of the drug molecule for binding to the extracellular matrix of lung cells

  4. similarity of the drug molecule to other molecules normally transported lung cells

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TLS Online TPP Program

#Question id: 12907

#XL - S Microbiology

The binding of a regulatory protein or transcription factor to a specific DNA site results in a complex which may be analyzed by the technique termed as _____

TLS Online TPP Program

#Question id: 12908

#XL - S Microbiology

Which statement is incorrect about CRISPR?

TLS Online TPP Program

#Question id: 12911

#XL - S Microbiology

Match the following:
A. DNA polymerases              i. Alkaline phosphatase        a.RNA-dependent DNA polymerase, used in cDNA synthesis
B. Reverse transcriptase        ii. T4 DNA ligase                    b. Thermostable DNA polymerase used in PCR
C. Ligases                                 iii.  AMV-RT                            c. Removes 5′-phosphates from DNA and RNA
D. Phosphatases                     iv. Taq DNA pol                      d. Links 5′-phosphate and 3′-hydroxyl ends via phosphodiester bond

TLS Online TPP Program

#Question id: 12912

#XL - S Microbiology

Name the enzyme which separates the double-helical DNA into single strands.

TLS Online TPP Program

#Question id: 12913

#XL - S Microbiology

________  involves the size analysis of restriction fragments produced by several restriction enzymes individually and in combination. 

TLS Online TPP Program

#Question id: 12914

#XL - S Microbiology

 In Electrophoresis of DNA the gel is first soaked in the alkali then it is transferred to the membrane so that the ________