TLS Online TPP Program

#Question id: 14969


 A new drug is developed that targets and binds to the lipid A portion of LPS from Gram negative bacterial cells. This drug shows a high degree of activity and binding in a test tube setting against purified lipid A. Based on this information,

#XL - S Microbiology
  1. We should fast track this drug and get it out to physicians immediately to help prevent toxic/septic shock in humans.
  2. We should do some animal testing with whole Gram-negative cells and the drug before we jump to any conclusions.
  3. We should next proceed by moving to testing in a test tube using whole Gram-negative cells to see if it binds with the same strength.
  4. We should abandon the drug entirely binding to lipid A won't kill the bacteria, so the drug is useless to develop further
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TLS Online TPP Program

#Question id: 31418

#XL - S Microbiology

Which nutritional group does a bacterium belong to if it obtains energy from a chemical source, with 𝐶𝑂2 as the principal carbon source, and an inorganic electron donor?

TLS Online TPP Program

#Question id: 31419

#XL - S Microbiology

Twitching motility in bacteria is primarily mediated by:

TLS Online TPP Program

#Question id: 31420

#XL - S Microbiology

In twitching motility, the retraction of Type IV pili is powered by:

TLS Online TPP Program

#Question id: 31421

#XL - S Microbiology

Which option(s) correctly match(es) the Adherence factor in a bacterial cell (Column I) with their corresponding functions (Column II). 

 COLUMN I COLUMN II
 P. Fimbriae i. Cell envelopes of some archaeobacteria that may promote adherence to surfaces 
 Q. Glycocalyx ii. help attach bacteria to other bacteria or to solid surfaces
 R. S layer iii. Cell wall components in gram-positive bacteria that aid in adhesion
 S. Teichoic acid iv. viscous (sticky) and gelatinous polymer

TLS Online TPP Program

#Question id: 31422

#XL - S Microbiology

Which type of bacteria have flagella spread evenly over their entire surface?

TLS Online TPP Program

#Question id: 31423

#XL - S Microbiology

Correctly match the bacterial type in Column I with their corresponding environmental niche in Column II.

 COLUMN I COLUMN II
 P. Psychrotrophs i. Can grow at 180°C or Higher
 Q. Thermophile ii. pH greater than 8
 R. Alkalophile iii. Optimum 30°C to maximum around 35°C
 S. Halophile iv. Growth more rapid at high hydrostatic pressure 
 v. Salt concentration greater than 2M