TLS Online TPP Program

#Question id: 3783


What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?

#XL - Q Biochemistry
  1. The origins of replication occur only at the 5′ end.

  2. Helicases and single-strand binding proteins work at the 5′ end.

  3. DNA polymerase can join new nucleotides only to the 3′ end of a pre-existing strand, and the strands are antiparallel.

  4. DNA ligase works only in the 3′ → 5′ direction.