TLS Online TPP Program

#Question id: 2250


Which of the following is true about cystic fibrosis?

#XL - Q Biochemistry
  1. The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP.

  2.  CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell.

  3. There are no treatments for patients with CF that are specifically targeted to the CFTR receptor.

  4. Patients with the most common mutation make a CFTR protein that is not present in the membrane.