TLS Online TPP Program

#Question id: 1363


Which of the following statements best describes the difference between low-affinity integrins and high-affinity integrins?

#XL - Q Biochemistry
  1. Many integrins can exist in two conformations: a low-affinity (bent) conformation and a high-affinity (straight) conformation.

  2. Dissociation of the alpha beta heterodimer converts many integrins from the low-affinity to the high-affinity state.

  3. Association of the alpha beta heterodimer converts many integrins from the low-affinity to the high-affinity state.

  4. Proteolytic cleavage of the C-terminal tails of the two subunits converts many integrins from the low-affinity to the high-affinity state.