In frogs, maternally packaged Xwnt-11 leads to nuclear localization of _____ in the _____, which in response signals to adjacent cells to become the _____.

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#Question id: 11210

#Unit 7. System Physiology – Animal

An inhibitory postsynaptic potential (IPSP) occurs in a membrane made more permeable to ________.

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#Question id: 1578

#Unit 4. Cell Communication and Cell Signaling

Function of TH2

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#Question id: 593

#Unit 1. Molecules and their Interaction Relevant to Biology

The time that is required for an enzyme to convert one substrate molecule into one product molecule is

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#Question id: 15306

#Unit 4. Cell Communication and Cell Signaling

The transformation of a normal cell to a cancer cell is accompanied  by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;

Gene	Primary tumor	Proposed function
i) APC	Colorectal	Binds β ‐catenin acting as transcription factor
ii) BRCA1	Breast	DNA repair
iii) MSH2, MLH1	Melanoma, pancreatic	p16: Cdk inhibitor ARF: stabilizes p53
iv) E‐Cadherin	Breast, colon	Cell adhesion molecule
v) INK4a	Colorectal	Mismatch repair
vi) NF1	Neurofibromas	Activates GTPase of Ras

Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions;

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#Question id: 594

#Unit 1. Molecules and their Interaction Relevant to Biology

The catalytic proficiency of an enzyme is the ________.