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TLS Online TPP Program

#Question id: 602

An inhibitor binds to a site other than the active site of the enzyme. Which statement below correlates with this observation?

#Unit 1. Molecules and their Interaction Relevant to Biology

  1. It must be a competitive inhibitor.

  2. The inhibition must be irreversible.

  3. It could be noncompetitive or uncompetitive inhibition.

  4. It could be irreversible, competitive, noncompetitive or uncompetitive. The data do not relate to the type of inhibition.

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TLS Online TPP Program

#Question id: 26505

#Unit 3. Fundamental Processes

Which of the splicing snRNPs is common in both major and minor
TLS Online TPP Program

#Question id: 26504

#Unit 3. Fundamental Processes

SR proteins are involved in exon definition in which they interact with U1 and U2AF forming the commitment for
TLS Online TPP Program

#Question id: 26503

#Unit 3. Fundamental Processes

Match the following

 Protein Function
 1. Prp 5 a. helps the release of the mature mRNA from the spliceosome 
 2. Brr 2 b. is responsible for the activation of the spliceosome
 3. Prp 2 c. facilitates U1 and U4 release
 4. Prp 22 d. is critical for U2 binding
TLS Online TPP Program

#Question id: 26502

#Unit 3. Fundamental Processes

Splice sites are directional in nature. 5’ splice site -the left, or donor, site and the 3’ splice site - right, or acceptor, site. So, in below table the complex and their events are given match them correctly .

 Column 1 Column 2
 1. E complex a. Joining of U4/6 and U5 tri-snRNPs
 2. A complex b. U2 addition to base pair with the branch site in the presence of ATP
 3. B1 complex c. Formation of commitment complex in which U1 is base paired with the 5' splice site 
TLS Online TPP Program

#Question id: 26501

#Unit 3. Fundamental Processes

Splice sites are directional in nature
TLS Online TPP Program

#Question id: 26500

#Unit 3. Fundamental Processes

Choose the correct statement 
1.UACUAAC is branch point sequence for U2 type introns 
2.UACUAAC is branch point sequence for U12 type introns
3.CCUUAAC is branch point sequence for U12 type introns
4.CCUUAAC is branch point sequence for U2 type introns