#Question id: 11554
#Unit 7. System Physiology – Animal
What happens in a cell when adenylyl cyclase is activated?
#Question id: 13176
#Unit 10. Ecological Principles
#Question id: 18079
#Unit 9. Diversity of Life Forms
#Question id: 1089
#Unit 4. Cell Communication and Cell Signaling
Which of the following statements describes a likely effect of a drug designed that inhibits the cellular response to testosterone?
#Question id: 879
#Unit 1. Molecules and their Interaction Relevant to Biology
Correct approaches to protein structure prediction-:
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i. Homology modeling |
a) Methods is the Rosetta program, formulated by David Baker. To satisfy the program’s computational needs, a volunteer network of ∼100,000 computers, known as Rosetta@home, provides the 500,000 or so hours of processing time required to generate a structure. |
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ii. Structural genomics |
b) which seeks to determine the X-ray structures of all representative domains, is aimed at expanding this predictive technique. The identification of structural homology is likely to provide clues as to a protein’s function even with imperfect structure prediction. |
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iii. Threading |
c) Is a computational technique that attempts to determine the unknown structure of a protein by ascertaining whether it is consistent with a known protein structure. It does so by placing the unknown protein’s residues along the backbone of a known protein structure and then determining whether the amino acid side chains of the unknown protein are stable in that arrangement |
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iv. Ab initio |
d) Aligns the sequence of interest with the sequence of a homologous protein or domain of known structure—compensating for amino acid substitutions, insertions, and deletions—through modeling and energy minimization calculations. |